Two-Step Barbecue Brisket

Directions

1. 1
   In mixing bowl, stir together chipotle powder, salt, sugar, garlic powder and onion powder.
2. 2
   Transfer beef to a large resealable plastic bag; add spice mixture and liquid smoke.
3. 3
   Seal bag and shake to coat meat.
4. 4
   Refrigerate 8 hours or overnight.
5. 5
   Heat oven to 250F.
6. 6
   Remove brisket from bag and place in broiler pan, fat side up.
7. 7
   Cook 2 1/2 to 3 hours, basting with juices every hour.
8. 8
   Let meat rest 15 minutes.
9. 9
   Cut against the grain into thin slices.
10. 10
    Pour pan juices over top.